Since its beginning in 2010, the CRC 850 conducts research in three interdependent research areas:
A. Control of cell movements in development,
B. Mechanisms of tumor cell invasion and metastasis
C. Translation to human cancer and novel therapeutic approaches.
All three research areas are strongly supported by the central projects, which provide multidisciplinary expertise and state-of-the-art infrastructure for the analysis of tumor biopsies and monitoring of tumor growth and metastatic spread. In addition, the CRC 850 hosts the integrated research training group (IRTG) with the mission to provide the doctoral (PhD and MD/PhD) students of the CRC with a structured environment promoting their skills and scientific education.
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Eckerle, S., M. Ringler, V. Lecaudey, R. Nitschke and W. Driever (2018). “Progesterone modulates microtubule dynamics and epiboly progression during zebrafish gastrulation.” Dev Biol 434(2): 249-266.
Fiala, G. J. and S. Minguet (2018). “Caveolin-1: The Unnoticed Player in TCR and BCR Signaling.” Adv Immunol 137: 83-133.