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Research

Publications

Duteil, D., Y. Tourette, A. Eberlin, D. Willmann, D. Patel, N. Friedrichs, J. M. Muller and R. Schule (2018). “The inhibitor of histone acetyltransferases Nir regulates epidermis development.” Development. doi: 10.1242/dev.158543.

Foll, M. C., M. Fahrner, C. Gretzmeier, K. Thoma, M. L. Biniossek, D. Kiritsi, F. Meiss, O. Schilling, A. Nystrom and J. S. Kern (2018). “Identification of tissue damage, extracellular matrix remodeling and bacterial challenge as common mechanisms associated with high-risk cutaneous squamous cell carcinomas.” Matrix Biol 66: 1-21.

Herr, R., S. Halbach, M. Heizmann, H. Busch, M. Boerries and T. Brummer (2018). “BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.” Oncogene 37(12): 1576-1593.

Mathew, N. R., F. Baumgartner, L. Braun, D. O’Sullivan, S. Thomas, M. Waterhouse, T. A. Muller, K. Hanke, S. Taromi, P. Apostolova, A. L. Illert, W. Melchinger, S. Duquesne, A. Schmitt-Graeff, L. Osswald, K. L. Yan, A. Weber, S. Tugues, S. Spath, D. Pfeifer, M. Follo, R. Claus, M. Lubbert, C. Rummelt, H. Bertz, R. Wasch, J. Haag, A. Schmidts, M. Schultheiss, D. Bettinger, R. Thimme, E. Ullrich, Y. Tanriver, G. L. Vuong, R. Arnold, P. Hemmati, D. Wolf, M. Ditschkowski, C. Jilg, K. Wilhelm, C. Leiber, S. Gerull, J. Halter, C. Lengerke, T. Pabst, T. Schroeder, G. Kobbe, W. Rosler, S. Doostkam, S. Meckel, K. Stabla, S. K. Metzelder, S. Halbach, T. Brummer, Z. Hu, J. Dengjel, B. Hackanson, C. Schmid, U. Holtick, C. Scheid, A. Spyridonidis, F. Stolzel, R. Ordemann, L. P. Muller, F. Sicre-de-Fontbrune, G. Ihorst, J. Kuball, J. E. Ehlert, D. Feger, E. M. Wagner, J. Y. Cahn, J. Schnell, F. Kuchenbauer, D. Bunjes, R. Chakraverty, S. Richardson, S. Gill, N. Kroger, F. Ayuk, L. Vago, F. Ciceri, A. M. Muller, T. Kondo, T. Teshima, S. Klaeger, B. Kuster, D. D. H. Kim, D. Weisdorf, W. van der Velden, D. Dorfel, W. Bethge, I. Hilgendorf, A. Hochhaus, G. Andrieux, M. Borries, H. Busch, J. Magenau, P. Reddy, M. Labopin, J. H. Antin, A. S. Henden, G. R. Hill, G. A. Kennedy, M. Bar, A. Sarma, D. McLornan, G. Mufti, B. Oran, K. Rezvani, O. Shah, R. S. Negrin, A. Nagler, M. Prinz, A. Burchert, A. Neubauer, D. Beelen, A. Mackensen, N. von Bubnoff, W. Herr, B. Becher, G. Socie, M. A. Caligiuri, E. Ruggiero, C. Bonini, G. Hacker, J. Duyster, J. Finke, E. Pearce, B. R. Blazar and R. Zeiser (2018). “Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.” Nature Medicine 24(3): 282-291.

Pastor, V. B., S. S. Sahoo, J. Boklan, G. C. Schwabe, E. Saribeyoglu, B. Strahm, D. Lebrecht, M. Voss, Y. T. Bryceson, M. Erlacher, G. Ehninger, M. Niewisch, B. Schlegelberger, I. Baumann, J. C. Achermann, A. Shimamura, J. Hochrein, U. Tedgard, L. Nilsson, H. Hasle, M. Boerries, H. Busch, C. M. Niemeyer and M. W. Wlodarski (2018). “Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.” Haematologica 103(3): 427-437.

Prestipino, A., A. J. Emhardt, K. Aumann, D. O’Sullivan, S. P. Gorantla, S. Duquesne, W. Melchinger, L. Braun, S. Vuckovic, M. Boerries, H. Busch, S. Halbach, S. Pennisi, T. Poggio, P. Apostolova, P. Veratti, M. Hettich, G. Niedermann, M. Bartholoma, K. Shoumariyeh, J. S. Jutzi, J. Wehrle, C. Dierks, H. Becker, A. Schmitt-Graeff, M. Follo, D. Pfeifer, J. Rohr, S. Fuchs, S. Ehl, F. A. Hartl, S. Minguet, C. Miething, F. H. Heidel, N. Kroger, I. Triviai, T. Brummer, J. Finke, A. L. Illert, E. Ruggiero, C. Bonini, J. Duyster, H. L. Pahl, S. W. Lane, G. R. Hill, B. R. Blazar, N. von Bubnoff, E. L. Pearce and R. Zeiser (2018). “Oncogenic JAK2(V617F) causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.” Science Translational Medicine 10(429).

Eckerle, S., M. Ringler, V. Lecaudey, R. Nitschke and W. Driever (2018). “Progesterone modulates microtubule dynamics and epiboly progression during zebrafish gastrulation.” Dev Biol 434(2): 249-266.

Fiala, G. J. and S. Minguet (2018). “Caveolin-1: The Unnoticed Player in TCR and BCR Signaling.” Adv Immunol 137: 83-133.

Muller, A. K., M. Foll, B. Heckelmann, S. Kiefer, M. Werner, O. Schilling, M. L. Biniossek, C. A. Jilg and V. Drendel (2018). “Proteomic Characterization of Prostate Cancer to Distinguish Nonmetastasizing and Metastasizing Primary Tumors and Lymph Node Metastases.” Neoplasia 20(2): 140-151.

Nystrom, A. and L. Bruckner-Tuderman (2018). “Injury- and inflammation-driven skin fibrosis: The paradigm of epidermolysis bullosa.” Matrix Biol. doi: 10.1016/j.matbio.2018.01.016.

Tosic, M., A. Allen, D. Willmann, C. Lepper, J. Kim, D. Duteil and R. Schule (2018). “Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.” Nature Communications 9(1): 366.

Thriene, K., B. A. Gruning, O. Bornert, A. Erxleben, J. Leppert, I. Athanasiou, E. Weber, D. Kiritsi, A. Nystrom, T. Reinheckel, R. Backofen, C. Has, L. Bruckner-Tuderman and J. Dengjel (2018). “Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes.” Mol Cell Proteomics. doi: 10.1074/mcp.RA117.000437.

Galiger, C., S. Loffek, M. P. Stemmler, J. K. Kroeger, V. R. Mittapalli, L. Fauth, P. R. Esser, J. S. Kern, F. Meiss, S. Lassmann, L. Bruckner-Tuderman and C. W. Franzke (2018). “Targeting of Cell Surface Proteolysis of Collagen XVII Impedes Squamous Cell Carcinoma Progression.” Mol Ther 26(1): 17-30.