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Research

Publications

Kohler I, Bronsert P, Timme S, Werner M, Brabletz T, Hopt UT, Schilling O, Bausch D, Keck T, Wellner UF (2015) Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma. J Gastroenterol Hepatol 30 Suppl 1: 78-84

Kern U, Wischnewski V, Biniossek ML, Schilling O, Reinheckel T (2015) Lysosomal protein turnover contributes to the acquisition of TGFbeta-1 induced invasive properties of mammary cancer cells. Mol Cancer 14: 39

Westphal P, Mauch C, Florin A, Czerwitzki J, Olligschlager N, Wodtke C, Schüle R, Buttner R, Friedrichs N (2015) Enhanced FHL2 and TGF-beta1 Expression Is Associated With Invasive Growth and Poor Survival in Malignant Melanomas. Am J Clin Pathol 143: 248-56; quiz 307

Lai ZW, Petrera A, Schilling O (2015c) Protein amino-terminal modifications and proteomic approaches for N-terminal profiling. Curr Opin Chem Biol 24: 71-9

Ronsch K, Jagle S, Rose K, Seidl M, Baumgartner F, Freihen V, Yousaf A, Metzger E, Lassmann S, Schüle R, Zeiser R, Michoel T, Hecht A (2015) SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer. Mol Oncol 9: 335-54

Al-Nomani L, Friedrichs J, Schüle R, Buttner R, Friedrichs N (2015) Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer. Pathol Res Pract 211: 171-4

Friedrichs J, Fink D, Mauch C, Kindler D, Hartmann W, Schüle R, Buettner R, Friedrichs N (2015) TGF-beta1-dependent induction and nuclear translocation of FHL2 promotes keratin expression in pilomatricoma. Virchows Arch 466: 199-208

Herr R and T Brummer (2015) BRAF inhibitors in colorectal cancer: Toward a differentiation therapy?, Molecular & Cellular Oncology, 2:4, e1002709, DOI:10.1080/23723556.2014.1002709

Kronig M, Walter M, Drendel V, Werner M, Jilg CA, Richter AS, Backofen R, McGarry D, Follo M, Schultze-Seemann W, Schüle R (2015) Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity. Oncotarget 6: 1302-14

Herr R, Kohler M, Andrlova H, Weinberg F, Moller Y, Halbach S, Lutz L, Mastroianni J, Klose M, Bittermann N, Kowar S, Zeiser R, Olayioye MA, Lassmann S, Busch H, Boerries M, Brummer T (2015) B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells. Cancer Res 75: 216-29

Ahrens TD, Timme S, Hoeppner J, Ostendorp J, Hembach S, Follo M, Hopt UT, Werner M, Busch H, Boerries M, Lassmann S (2015) Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine. Epigenetics 10: 431-45

Seubert B, Grunwald B, Kobuch J, Cui H, Schelter F, Schaten S, Siveke JT, Lim NH, Nagase H, Simonavicius N, Heikenwalder M, Reinheckel T, Sleeman JP, Janssen KP, Knolle PA, Kruger A (2015) Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice. Hepatology 61: 238-48

Bedzhov I, Stemmler MP (2015) Applying the proximity ligation assay (PLA) to mouse preimplantation embryos for identifying protein-protein interactions in situ. Methods Mol Biol 1233: 57-64

Kuales G, Weiss M, Sedelmeier O, Pfeifer D, Arnold SJ (2015) A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence. Stem Cells Int 2015: 218518