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Research

Publications

Willmann L, Erbes T, Halbach S, Brummer T, Jager M, Hirschfeld M, Fehm T, Neubauer H, Stickeler E, Kammerer B (2015) Exometabolom analysis of breast cancer cell lines: Metabolic signature. Sci Rep 5: 13374

Nilse L, Sigloch FC, Biniossek ML, Schilling O (2015) Toward improved peptide feature detection in quantitative proteomics using stable isotope labeling. Proteomics Clin Appl 9: 706-14

Weisser J, Lai ZW, Bronsert P, Kuehs M, Drendel V, Timme S, Kuesters S, Jilg CA, Wellner UF, Lassmann S, Werner M, Biniossek ML, Schilling O (2015) Quantitative proteomic analysis of formalin-fixed, paraffin-embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines. BMC Genomics 16: 559

Jank T, Eckerle S, Steinemann M, Trillhaase C, Schimpl M, Wiese S, van Aalten DM, Driever W, Aktories K (2015) Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos. Nat Commun 6: 7807

Lai ZW, Gomez-Auli A, Keller EJ, Mayer B, Biniossek ML, Schilling O (2015a) Enrichment of protein N-termini by charge reversal of internal peptides. Proteomics 15: 2470-8

Tholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, Stickeler E, Rospert S, Reinheckel T (2015) Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. J Biol Chem 290: 15758-69

Mock K, Preca BT, Brummer T, Brabletz S, Stemmler MP, Brabletz T (2015) The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors. Oncotarget 6: 14399-412

Alotaibi H, Basilicata MF, Shehwana H, Kosowan T, Schreck I, Braeutigam C, Konu O, Brabletz T, Stemmler MP (2015) Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition. Biochim Biophys Acta 1849: 731-42

Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schuler J, Berthold M, Weber A, Burk U, Lubbert M, Puhr M, Culig Z, Wellner U, Keck T, Bronsert P, Kusters S, Hopt UT, Stemmler MP, Brabletz T (2015) ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med 7: 831-47

Haug S, Schnerch D, Halbach S, Mastroianni J, Dumit VI, Follo M, Hasenburg A, Kohler M, Dierbach H, Herzog S, Proske A, Werner M, Dengjel J, Brummer T, Lassmann S, Wäsch R, Zeiser R (2015) Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer. Int J Cancer 136: 2328-40

Hurskainen T, Kokkonen N, Sormunen R, Jackow J, Loffek S, Soininen R, Franzke CW, Bruckner-Tuderman L, Tasanen K (2015) Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice. J Invest Dermatol 135: 1303-10

Boerries M, Herr R, Brummer T, Busch H (2015) Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines. Genom Data 4: 158-61

Pfaumann V, Lang AE, Schwan C, Schmidt G, Aktories K (2015) The actin and Rho-modifying toxins PTC3 and PTC5 of Photorhabdus luminescens: enzyme characterization and induction of MAL/SRF-dependent transcription. Cell Microbiol 17: 579-94

Franz H, Greschik H, Willmann D, Ozretic L, Jilg CA, Wardelmann E, Jung M, Buettner R, Schüle R (2015) The histone code reader SPIN1 controls RET signaling in liposarcoma. Oncotarget 6: 4773-89

Lai ZW, Petrera A, Schilling O (2015b) The emerging role of the peptidome in biomarker discovery and degradome profiling. Biol Chem 396: 185-92

Moilanen JM, Kokkonen N, Loffek S, Vayrynen JP, Syvaniemi E, Hurskainen T, Makinen M, Klintrup K, Makela J, Sormunen R, Bruckner-Tuderman L, Autio-Harmainen H, Tasanen K (2015) Collagen XVII expression correlates with the invasion and metastasis of colorectal cancer. Hum Pathol 46: 434-42